Reading difficulty is associated with failure to lateralize temporooccipital function

C Tailby; DL Weintrob; MM Saling; C Fitzgerald; GD Jackson

Journal article

Reading difficulty is associated with failure to lateralize temporooccipital function

C Tailby, DL Weintrob, MM Saling, C Fitzgerald, GD Jackson

Epilepsia | WILEY-BLACKWELL | Published : 2014

DOI: 10.1111/epi.12607

Abstract

Objective Studies of focal epilepsy have revealed abnormalities of language organization; however, little attention has been paid to disorders of reading in this group. We hypothesized that language functional magnetic resonance imaging (fMRI) would reveal differences in language organization between focal epilepsy patients with and without reading difficulties. Methods We conducted language fMRI studies of 10 focal epilepsy patients with reading difficulties, 34 focal epilepsy patients without reading difficulties, and 42 healthy controls. Results We defined regions of interests on the basis of activation patterns on an orthographic lexical retrieval task. Comparison of activations within t..

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University of Melbourne Researchers

Chris Tailby Author

Michael Saling Author

Graeme Jackson Author

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Grants

Awarded by National Institute of Neurological Disorders and Stroke

Funding Acknowledgements

We thank all the patients and healthy controls who participated in this project. This study was supported by the National Health and Medical Research Council of Australia program grant (628952) and an NHMRC practitioner fellowship to GDJ (527800), NHMRC Project grants 368650, 318900, and 628725, and the Operational Infrastructure Support Program of the State Government of Victoria, Australia.